Children’s Health

Northwestern Medicine scientists have characterized several variants of the gene GRIK2 that cause nonsyndromic neurodevelopmental disorder (NDD), according to a study published in the American Journal of Human Genetics. These findings add two new genetic variants to a growing list of glutamate receptor mutations that can cause neurodevelopmental disorders, according to Geoffrey Swanson, PhD, professor
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Results from a 10-year study of children and adolescents who underwent a common weight loss operation to treat severe obesity show they safely have long-lasting major weight loss and improvement of their obesity-related medical problems without stunting their growth in height. The study, involving the longest known follow-up of pediatric patients after laparoscopic sleeve gastrectomy,
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In a study with mice reported today in the journal Science Translational Medicine, a Johns Hopkins Medicine research team has provided what may be the most definitive view to date of the biological process leading to necrotizing enterocolitis (NEC), a dangerous inflammatory disease that can destroy a premature infant’s intestinal lining and causes death in
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Researchers at Baylor College of Medicine and Texas Children’s Hospital have uncovered a potential Achilles heel of acute myeloid leukemia (AML) in children that could lead to new treatments for this devastating disease. The team was the first to identify specific super-enhancers (SE) – regions of DNA that drive the overproduction of certain gene products
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A common antibiotic has been found to reduce low birth weight and premature births, if taken during pregnancy, in countries where malaria is endemic, according to a research review. The systematic review, led by the Murdoch Children’s Research Institute (MCRI) and published in The Lancet EClinicalMedicine, found that the antibiotic, azithromycin, reduced low birth weight
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A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced a variety of cardiovascular disease risks. The study, which was published today in the Journal of Clinical Pediatrics, paired parents and children together throughout the trial. According to the Center for Disease Control and
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Researchers in the United States have conducted a study showing that the antibody response to vaccination designed to protect against coronavirus disease 2019 (COVID-19) wanes substantially over time among patients receiving maintenance dialysis. The team’s study of more than 1,500 individuals found that antibody titers against the COVID-19 causative agent – severe acute respiratory syndrome
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A parent-led therapy that supports the social development of babies displaying early signs of autism has significantly reduced the likelihood of an autism diagnosis being made in early childhood, according to world-first research led by CliniKids atthe Telethon Kids Institute. In a study published in JAMA Pediatrics, an international research team led by Professor Andrew
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Allergic reactions to the new mRNA-based COVID-19 vaccines are rare, typically mild and treatable, and they should not deter people from becoming vaccinated, according to research from the Stanford University School of Medicine. The findings will be published online Sept. 17 in JAMA Network Open. We wanted to understand the spectrum of allergies to the
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Patients with intellectual and developmental disabilities (IDD) are three times more likely to die from COVID-19 than the general population. Their heightened risk is due to a variety of causes: pre-existing health conditions, such as respiratory problems or obesity; increased likelihood of living in group homes, taking shared transportation, and being exposed to people outside
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Eighteen months into the covid-19 pandemic, with the delta variant fueling a massive resurgence of disease, many hospitals are hitting a heartbreaking new low. They’re now losing babies to the coronavirus. The first reported covid-related death of a newborn occurred in Orange County, Florida, and an infant has died in Mississippi. Merced County in California
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Six stages of engagement in treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) have been reported by researchers at Boston Medical Center based on a diverse study, inclusive of parents of predominantly racial and ethnic minority children with ADHD. Published in Pediatrics, this new framework has been informed by the experiences of parents throughout the various stages that
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In a systematic review, researchers assessed the diagnostic value of certain physical symptoms that children may display that could indicate a urinary tract infection. The team performed literature reviews of the most prominent medical research databases from inception until Jan. 20, 2020 for studies reporting specific diagnostic accuracy data for clinical signs and symptoms compared
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The initial period of the coronavirus disease 2019 (COVID-19) pandemic did not seriously affect children partly due to their relative isolation from sources of infection via school closures. However, the delta variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is currently spreading has affected children more than that initial period. Study: The
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Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection typically affects children only mildly, multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS) is a serious but rare complication occurring after infection. PIMS or MIS-C symptoms in affected children PIMS or MIS-C usually occurs 2 to 6 weeks after SARS-CoV-2 infection, and
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Hospitalized COVID-19 patients are substantially more likely to harbor autoantibodies -;antibodies directed at their own tissues or at substances their immune cells secrete into the blood -; than people without COVID-19, according to a new study. Autoantibodies can be early harbingers of full-blown autoimmune disease. If you get sick enough from COVID-19 to end up
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